57XP
Higher aerobic fitness goes with a much lower risk of early death in large studies, though these cannot prove cardio is the cause.
Aging
Healthy Aging
Supplements and protocols ranked by XP
45XP
Adults who took about 6,000 to 11,000 steps a day had a 40–53% lower risk of dying during follow-up than those taking about 3,500, with benefits levelling off at 6,000–8,000 steps for over-60s and 8,000–10,000 for younger adults.
34XP
People who eat the most fibre have a 15–30% lower risk of early death, heart disease, stroke and type 2 diabetes than those who eat the least, with the largest benefit at 25–29 g a day.
27XP
In large studies, people with irregular sleep times had a higher risk of early death, but these show a link, not proof that a steadier schedule is the cause.
Studies1
21XP
A 2018 meta-analysis of 30 cohort studies (225,600 deaths) found higher Mediterranean-diet adherence associated with meaningfully lower all-cause mortality, with a dose-response relationship (greater adherence, greater reduction) — one of the most consistently replicated findings in nutrition epidemiology.
Studies1
21XP
Across 16 large cohort studies, people who did muscle-strengthening activity had a 10-17% lower risk of all-cause mortality, cardiovascular disease, total cancer and diabetes, independent of aerobic activity, with the biggest risk reduction at about 30-60 minutes a week.
Studies1
20XP
A 2015 meta-analysis and a 2023 meta-analysis of 90 cohort studies (2.2 million people) both found social isolation and loneliness associated with meaningfully higher all-cause mortality (roughly 14–34% higher risk depending on the measure), an effect size comparable to other well-established mortality risk factors.
15XP
People who eat the most ultra-processed food have higher rates of heart disease death and type 2 diabetes in long-term studies, though this kind of evidence cannot prove cause.
11XP
In a 20-year study of 2,315 Finnish men, those using a sauna 4–7 times a week died at a lower rate (31%) than those going once a week (49%), though this cannot prove the sauna was the cause.
8XP
Raises NAD+ levels, but clear everyday benefits have not been shown yet.
