19XP
In a single small randomised trial, CoQ10 reduced migraine attack frequency more than placebo, but this has not been well replicated.
Studies1

In a single small randomised trial, CoQ10 reduced migraine attack frequency more than placebo, but this has not been well replicated.

Fewer migraines at high doses (about 600 mg), recognised by neurology guidelines as probably effective.

May reduce headache days a little in people with migraine; trials are small.

A single trial suggested that drinking more water may help people with recurrent headaches, but this has not been confirmed.
